At our clinical
research unit in Plymouth, Veeda have
established an excellent reputation for
conducting complex CNS studies. The addition
of our Ahmedabad phase I unit in India
provides unrivalled access to patient
populations for the rapid and efficient
conduct of early phase and POC studies in a
range of CNS disorders.
Experience &
Expertise
Cognitive testing is one of the tools
available in translational medicine in the
development of CNS therapeutic agents. Veeda
have over 20 years experience in applying a
wide range of cognitive and neurological
test batteries to Phase I clinical research.
One of the specialities of Veeda’s unit in
Plymouth is safety and efficacy measurements
of anaesthetic agents. These studies involve
a wide range of assessments including EEG
technology and assessment of saccadic eye
movements
Some examples of some recent
studies performed in our unit are:
A study examining elderly male and
female subjects using Cambridge
Cognition (CANTAB): auditory verbal
learning test; spatial planning tests;
National Adult Reading Test.
A large
scale trial of age matched elderly
subjects classed into normal and with
mild cognitive impairment, compared with
young normal subjects, simultaneously
using the CANTAB and Cognitive Drug
Research (CDR) test batteries.
An elderly male and female study
employing the i3 research Computerized
Neuropsychological Test Battery (CNTB),
a battery of 11 tests that assessed:
motor speed; attention; information
processing; episodic memory (immediate
and delayed); procedural memory; spatial
memory; language; spatial function;
executive function.
An elderly male and female study
using CNTB - VSRT, SRT, CRT VAS, DSST.
A healthy young male volunteer study
using immediate and delayed word recall,
Karolinska sleepiness scale, full and
targeted neurological examinations.
A healthy male and female study
employing CDR: saccadic eye movements,
immediate and delayed word recall, digit
vigilance, choice reaction time, spatial
and numeric working memory, word
recognition, tracking and postural
stability.
A healthy young male study using
CogState: Groton maze learning test, one
card learning task, detection task,
identification task, controlled oral
word association test
Veeda’s unit
in Ahmedabad, India is
associated with the prestigious Gujarat
Imaging Centre. The centre offers 14
radiologists of differing specialty, most of
whom are western trained. The centre offers
the following capabilities:
Ultrasound imaging centre allowing
all modes of imaging and colour flow
visualisation
GE Medical Gamma Camera providing
for a range of scintigraphy and dynamic
studies.
Sumitomo Clinical Cyclotron for PET
– CT
Patient
Studies
Unrivalled access to elderly volunteer and
patient populations at our Plymouth site has
enabled us to conduct studies comparing
patients with healthy age matched subjects
in a range of studies examining CNS
compounds. Veeda currently has a database of
around 800 active male and female elderly
subjects (aged 65-85 years).
Veeda’s Plymouth unit also has access to
specific patient groups through consultants
and our local network of general
practitioners. The South West of England is
home to 11.5% of the UK’s Alzheimer’s
population giving Veeda access to more than
65,000 patients with this condition. In the
planning of Alzheimer’s studies Veeda works
closely with Professor Robin Eastwood FRC
Psych , FRCPc, FRCPE, Consultant
psychiatrist at the Nuffield Hospital,
Plymouth. Prof. Eastwood has published over
190 papers, book chapters and book reviews,
and was Editor-in-Chief of the
“International Psychogeriatrics” Journal
from 1996 – 2003.
Our UK unit has established an excellent GP
network which gives us access to around
50,000 patients. This network, together with
our links to consultants and hospitals in
the region, allows us access to patients
with a wide range of conditions including
Parkinson’s, Multiple Sclerosis and many
others.
The Advantage
of India
The prevalence and presentation of
psychiatric disorders in India is very
similar to that found in the West. The
prevalence of major psychiatric disorders in
India is in the region of 65 per 1000 people
in the population, giving an estimated 75.5
million patients fitting into this category.
This places our Ahmedabad clinical unit in
an ideal location to run early phase POC
studies in this therapeutic area.
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