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Centre of Excellence for Analytics & Characterization

Analytics and characterization department at Biopharma Division of Veeda is a preferred solution partner for physicochemical, structural characterization, and analytical CMC support for a broad range of biotherapeutics including peptides, oligos, recombinant-conjugated -fusion proteins, monoclonal antibodies (mAbs), bispecific antibody fragments, antibody-drug conjugates, and biopolymers.

Expert Characterization for Biopharmaceuticals: From Glycosylated Proteins to Vaccines, We Deliver Precision

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Monoclonal Antibody Characterization

Unlock the complexities of monoclonal antibody analysis with our specialized services in intact mass, peptide mapping, and glycopeptide analysis. Dive into our expertise in disulfide mapping, N-Glycan analysis, and structural integrity assessments — essential for biosimilarity and comparability studies.

Primary Structure

Discover top-tier protein characterization with Veeda Group. Our expert scientists offer detailed analyses, from liquid chromatography to peptide sequencing, providing essential insights into amino acid composition, purity, and variants. With our advanced technologies, we deliver precision and excellence to propel your biopharmaceutical development forward.

Higher-Order Structure (HOS)

Explore our advanced methodologies in spectroscopy, calorimetry, and light scattering to uncover insights into tertiary and quaternary protein structures. Our expertise in protein conformers and secondary structure analysis offers a deeper understanding of your biopharmaceutical’s stability and functionality.

Typical Development Path for HOS Monitoring in Biotherapeutics

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Navigate the stages of biopharmaceutical development with confidence using our comprehensive analytical support. From cell line selection to drug product testing, our services are designed to streamline your product’s journey to market approval.

Innovative ZipChip Collaboration Enhancing Precision In Charge Variant Characterization

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Analytical CMC Services -Biopharma

CMC analytical testing is a critical component of all drug development programs. These sophisticated assays monitor drug manufacturing processes to ensure the safety, efficacy, and quality of pharmaceutical products. Recognizing the inherent complexity of CMC bioanalytical strategies, our services are meticulously tailored to meet the specific needs of each therapeutic program, providing you with the confidence and assurance needed for successful regulatory approval.

N-Glycan Analysis in 3-4 Days

  • Fully automated for rapid results
  • Cutting down processing time from weeks to days

Cell Line/Clone Selection

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  • Protein sequence
  • Sequence variants characterization
  • PTM analysis
  • Glycosylation analysis
  • De novo sequencing

Upstream

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  • Harvest titers
  • Identity
  • Purity
  • Glycosylation analysis
  • PTM analysis

Downstream

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  • Size/charge variants
  • Refolding efficiency
  • Identity
  • Purity
  • Heterogeneity
  • Impurity
  • N-/O-glycans
  • Residuals (HCD, HCP, rProA)
  • Potency

Formulation

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  • PTM quantification
  • Monitoring degradation
  • Excipient testing
  • MAM-based monitoring of selected PTMs
  • Studies on formulants role in protein stability

Drug Substance & Drug Product (DS & DP)

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  • DS & DP Testing
  • Identity
  • Purity
  • Heterogeneity
  • Intact mass
  • Peptide map
  • Glycan analysis
  • Residuals
  • Potency

State-of-the-Art Veeda Biopharma Analytical Technologies

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PA800 PLUS

Chirascan V100

INVENIO

Prominence LC

BioPharma Finder

Circular Dichroism Spectroscopy (CD)

Water Connect

AF2000 Modular SEC & FFF MALS

Litesizer

nanoDSC

QExactive Orbitrap

Xevo G3 QT

ZipChip CE-MS Device