Centre of Excellence for Analytics & Characterization
Analytics and characterization department at Biopharma Division of Veeda is a preferred solution partner for physicochemical, structural characterization, and analytical CMC support for a broad range of biotherapeutics including peptides, oligos, recombinant-conjugated -fusion proteins, monoclonal antibodies (mAbs), bispecific antibody fragments, antibody-drug conjugates, and biopolymers.
Expert Characterization for Biopharmaceuticals: From Glycosylated Proteins to Vaccines, We Deliver Precision
Primary Structure
Discover top-tier protein characterization with Veeda Group. Our expert scientists offer detailed analyses, from liquid chromatography to peptide sequencing, providing essential insights into amino acid composition, purity, and variants. With our advanced technologies, we deliver precision and excellence to propel your biopharmaceutical development forward.
Higher-Order Structure (HOS)
Explore our advanced methodologies in spectroscopy, calorimetry, and light scattering to uncover insights into tertiary and quaternary protein structures. Our expertise in protein conformers and secondary structure analysis offers a deeper understanding of your biopharmaceutical’s stability and functionality.
Innovative ZipChip Collaboration Enhancing Precision In Charge Variant Characterization
CMC analytical testing is a critical component of all drug development programs. These sophisticated assays monitor drug manufacturing processes to ensure the safety, efficacy, and quality of pharmaceutical products. Recognizing the inherent complexity of CMC bioanalytical strategies, our services are meticulously tailored to meet the specific needs of each therapeutic program, providing you with the confidence and assurance needed for successful regulatory approval.
N-Glycan Analysis in 3-4 Days
- Fully automated for rapid results
- Cutting down processing time from weeks to days
Cell Line/Clone Selection
- Protein sequence
- Sequence variants characterization
- PTM analysis
- Glycosylation analysis
- De novo sequencing
Upstream
- Harvest titers
- Identity
- Purity
- Glycosylation analysis
- PTM analysis
Downstream
- Size/charge variants
- Refolding efficiency
- Identity
- Purity
- Heterogeneity
- Impurity
- N-/O-glycans
- Residuals (HCD, HCP, rProA)
- Potency
Formulation
- PTM quantification
- Monitoring degradation
- Excipient testing
- MAM-based monitoring of selected PTMs
- Studies on formulants role in protein stability
Drug Substance & Drug Product (DS & DP)
- DS & DP Testing
- Identity
- Purity
- Heterogeneity
- Intact mass
- Peptide map
- Glycan analysis
- Residuals
- Potency